Fourteen-day sequential therapy is superior to 7-day triple therapy as first-line regimen for Helicobacter pylori infected children
نویسندگان
چکیده
منابع مشابه
One-day quadruple therapy compared with 7-day triple therapy for Helicobacter pylori infection.
BACKGROUND Eradication of Helicobacter pylori infection has had an impact on the treatment and recurrence rates of peptic ulcer disease and malignancies such as mucosa-associated lymphoid tissue lymphoma. Treatment options are cumbersome, expensive, and associated with side effects. METHODS Randomized, prospective, open-labeled equivalence trial with a parallel-group design to compare eradica...
متن کامل1-day quadruple therapy was not inferior to 7-day triple therapy for eradication of Helicobacter pylori infection in dyspepsia.
P a t i e n t s 160 patients ≥ 18 years of age (mean age 50 y, 57% women) with dyspepsia and H. pylori infection who had a Glasgow Dyspepsia Severity Score (GDSS) of ≥ 3 (score range 0 to 20) and a positive carbon 14 urea breath test result. Exclusion criteria included previous treatment of H. pylori infection, pregnancy, personal or family history of gastrointestinal malignancy, antibiotic the...
متن کاملHelicobacter pylori eradication: A randomised comparative trial of 7-day versus 14-day triple therapy.
Background. Helicobacter pylori is associated with several upper gastrointestinal conditions including chronic gastritis, peptic ulcer disease, and gastric malignancy. Proton pump inhibitor-based triple therapies are considered the standard regimens for H. pylori eradication, but the optimal duration of therapy is controversial. To prevent infection and complications, local studies should be un...
متن کامل10-day sequential therapy was more effective than 10-day triple-drug therapy for eradicating Helicobacter pylori infection.
M e t h o d s Design: Randomized controlled trial. Allocation: {Concealed}†.* Blinding: Blinded (patients, investigators, {data collectors, outcome assessors, data analysts, and safety and monitoring committee}†).* Follow-up period: 8 weeks. Setting: 2 hospitals in Bologna and Rome, Italy. Patients: 300 patients ≥ 18 years of age (mean age 49 y, 64% women) with dyspepsia or peptic ulcers who ha...
متن کاملAddition of clidinium-C to the 14-day proton-pump inhibitor-based triple therapy for Helicobacter pylori eradication
Background: Triple therapy with a proton pump inhibitor and two antibiotics in Helicobacter pylori (HP) eradication is widely accepted, but this combination fails in a considerable number of cases. The aim of this study was to assess the effect of clidinium-C addition on HP eradication and to investigate the efficacy and safety of clidinium-C in prevention of drugs' side effects. Methods: A ...
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ژورنال
عنوان ژورنال: Journal of the Formosan Medical Association
سال: 2021
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2021.03.001